Blätter-Navigation

Of­f­re 72 sur 95 du 30/04/2020, 08:10

logologo

Tech­ni­sche Uni­ver­si­tät Dres­den - Cen­ter for Mole­cu­lar and Cel­lu­lar Bio­en­gi­nee­ring, Cen­ter for Mole­cu­lar Bio­en­gi­nee­ring (B CUBE), Chair of BioN­ano-Tools

The TU Dres­den is one of ele­ven Ger­man uni­ver­si­ties that were iden­ti­fied as an “excel­lence uni­ver­sity”. TUD has about 36.500 stu­dents and almost 5319 employees, 507 pro­fes­sors among them, and, thus, is the lar­gest uni­ver­sity in Sax­ony, today.

Having been com­mit­ted to sci­en­ces and the engi­nee­ring before the reuni­fi­ca­tion of Ger­many, TU Dres­den now is a multi-disci­pline uni­ver­sity, also offe­ring huma­nities and social sci­en­ces as well as medi­cine.

Rese­arch Asso­ciate / Early Stage Rese­arch

The posi­tion is offe­red for the EU-fun­ded MSC-ITN pro­ject on the topic “Coope­ra­tive effects in bio­mole­cu­lar trans­port sys­tems based on cou­pled motors”, star­ting 1st of Sep­tem­ber, 2020 for 36 mon­ths. The period of employ­ment is gover­ned by the Fixed Term Rese­arch Con­tracts Act (Wis­sen­schafts­zeit­ver­trags­ge­setz - WissZeitVG).
The pro­ject is fun­ded by the MARIE SKŁO­DOW­SKA CURIE Inno­va­tive Trai­ning Net­work (ITN) Arti­fi­cial Mole­cu­lar Machi­nes (Art­MoMa) wit­hin the Hori­zon 2020 Pro­gramme of the European Com­mis­sion [https://cordis.europa.eu/project/rcn/224720]. ITN Art­MoMa, a con­sor­tium of 20 part­ners com­po­sed of high pro­file uni­ver­si­ties, rese­arch insti­tu­ti­ons and com­pa­nies loca­ted in 8 European coun­tries, will train 15 ESRs (doc­to­ral stu­dents) in a highly inno­va­tive and inter­di­sci­pli­nary sci­en­ti­fic net­work. Sci­en­ti­fi­cally, ITN Art­MoMa will explore ways in which con­trol­led mecha­ni­cal move­ments of mole­cu­les can be orches­tra­ted and used in nanos­cale sys­tems. It will extend sci­en­ti­fic bounda­ries and explore ent­i­rely new direc­tions of fun­da­men­tal rese­arch towards tech­no­lo­gi­cally rele­vant imple­men­ta­ti­ons, for example in the fields of medi­cal tre­at­ment, mate­rial design, and energy con­ver­sion.
The par­ti­cu­lar pro­ject (ESR n°9) car­ried out in the rese­arch group of Prof. Ste­fan Diez at B CUBE (http://www.tu-dresden.de/bcube/diez, please feel wel­come to con­tact stefan.diez@tu-dresden.de for fur­ther infor­ma­tion), will explore coope­ra­tive effects in bio­mole­cu­lar trans­port sys­tems. In par­ti­cu­lar, it is envi­soned to study in vitro the velo­city and force out­put of micro­tu­bule-based trans­port sys­tems where several motors collec­tively trans­port a cargo. It will be of inte­rest to study the influ­ence of the motor cou­pling (soft vs. rigid) and the influ­ence of the micro­tu­bule sur­face (road­blocks and post-trans­la­tio­nal modi­fi­ca­ti­ons).

Work­ing field:

bio­che­mi­cal pre­pa­ra­tion of motors pro­te­ins; setup of in vitro moti­lity assays (in step­ping and gli­ding geo­me­try); deve­lop­ment of stra­te­gies to mecha­ni­cally couple mole­cu­lar motors; dyna­mic acqui­si­tion of motor-dri­ven cargo move­ment by high-reso­lu­tion fluo­re­scence micro­scopy and opti­cal tweezers; quan­ti­ta­tive image pro­ces­sing, data ana­ly­sis and mode­ling.

Require­ments:

uni­ver­sity degree (MSc degree or equi­va­lent) in (bio)phy­sics, (bio)che­mi­stry or (bio)nano­en­gi­nee­ring. App­li­cants should be ambi­tious, curious, crea­tive, ener­ge­tic and bright minds with a strong eager­ness to take part in the rese­arch and trai­ning activi­ties of this pro­ject and have excel­lent Eng­lish skills. Can­di­da­tes will be inte­gra­ted in an inter­na­tio­nal multi-disci­pli­nary team and shall the­re­fore have excel­lent per­so­nal skills and be able to work in a team. App­li­cants may be of any natio­na­lity. At the date of recruit­ment, the app­li­cant must not have resi­ded or car­ried out his/her main activity (work, stu­dies etc.) in Ger­many for more than 12 mon­ths in the last 3 years imme­dia­tely prior to his/her recruit­ment. App­li­cants must, at the date of recruit­ment, have NOT yet been awar­ded the doc­to­ral degree and have to be in the first 4 years (full time equi­va­lent) of their rese­arch career.

How to ap­ply:

The pos­i­tion will be loc­ated in Dresden, Ger­many. Second­ments to inter­na­tional part­ner groups are envi­sioned. The ESR will receive a salary accord­ing to MCSA reg­u­la­tion, includ­ing a liv­ing allow­ance, a mobil­ity allow­ance and a fam­ily allow­ance (if eli­gible). Applic­a­tions from women are par­tic­u­larly wel­come. The same applies to people with dis­ab­il­it­ies.
Please sub­mit your com­plete applic­a­tion with a motiv­a­tion let­ter, CV, pub­lic­a­tion list, two ref­er­ence let­ters and must be received by 29th of May 2020 (stamped arrival date applies) to TU Dresden, B CUBE, Pro­fes­sur für BioN­ano-Werkzeuge, Herrn Prof. Stefan Diez, Tatzberg 41, 01307 Dresden, Ger­many or via the TU Dresden Secure­Mail Portal https://securemail.tu-dresden.de by send­ing it as a single pdf doc­u­ment to stefan.diez@tu-dresden.de. Please sub­mit cop­ies only, as your applic­a­tion doc­u­ments will not be returned to you. Expenses incurred in attend­ing inter­views can­not be reim­bursed,

Ref­er­ence to data pro­tec­tion: Your data pro­tec­tion rights, the pur­pose for which your data will be pro­cessed, as well as fur­ther inform­a­tion about data pro­tec­tion is avail­able to you on the web­site: https://tu-dresden.de/karriere/datenschutzhinweis?set_language=en